Rapid diagnostic for bacterial infections
Université Libre de Bruxelles
Biochemistry; Beer; Spirits; Wine; Vinegar; Microbiology; Enzymology; Mutation Or Genetic Engineering
Demazy Lena [Be]; Smeesters Pierre [Be]; Van Melderen Laurence [Be]; Dreze Pierre Alexandre [Be]
About the technology
New fast technique for extraction and detection of bacterial RNA like pneumocoques or otitis in patient blood by quantitative PCR (qPCR).
Our laboratory has developed a new technique for extraction and detection of bacterial RNA in patient blood by quantitative PCR (qPCR). The value of this promising technique has been evaluated on 117 patients with pneumonia. While the classical diagnostic test for such infection (Blood culture) only allowed identifying the bacteria in 16% of the patients, our new diagnostic test detected the presence of bacterial RNA in 52% of them. Further improvements of the test are being made to allow for the detection of a broader array of bacterial pathogens and their antibiotic resistance profiles.
- Rapid diagnostic (2 hours versus 48 hours with the classical diagnostic)
- Detect more cases (better sensitivity)
- Simultaneous detection of antibiotic resistance profile
About the Research Organization
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